Brain TechBio 🧠🖥️ (ΙIΙ)
You can find the first and second part of this newsletter here 👉
Where Biology Meets Neural Tech: Brain wearables (Electroencephalography/EEG Headsets, Brain-Sensing Earbuds/Hearables, and Consumer Brain-Computer Interfaces, BCIs),
Leading BCI Startups,
Digital therapeutics (DTx) and AI solutions for Brain Health,
Other Neural Monitoring Wearable Startups.
Brain wearables, brain-sensing earbuds/hearables, and consumer Brain-Computer Interfaces,
TechBio Companies Advancing Brain Health,
Where Biology Meets Neural Tech: Put On The Map 🗺️ (US, Spain, UK, France, Portugal, Switzerland).
The third part of Brain TechBio 🧠🖥️ (ΙIΙ) is all about:
Where Biology Meets Neural Tech: Latest News,
Where Biology Meets Neural Tech: Put On The Map 🗺️ (Canada, Ireland, Sweden, Norway, Denmark, Italy),
Brain Automated Image Diagnostics From Europe, and
Brain Organoids.
Where Biology Meets Neural Tech
Latest News
Ιtaly’s Angelini Pharma signed on February 23, 2026 a multi-year research collaboration and licensing agreement with Massachusetts-based technology-driven Quiver Bioscience to discover 🆕 treatments for genetic epilepsies, including developmental and epileptic encephalopathies (Angelini partners with Quiver on AI-driven discovery in genetic epilepsies). Under the agreement, Quiver could receive up to $120M in milestone payments plus royalties if Angelini advances drug targets emerging from the collaboration. Financial terms for the upfront payment were not disclosed. Angelini will also receive exclusive access to data generated during the research term.
✅ Quiver’s “Genomic Positioning System” (GPS) platform leverages scalable human neuronal electrophysiology data alongside AI and ML to uncover new insights into disease biology.
✅ Quiver’s technology is built around human neuronal models and large-scale electrophysiological measurements. The company generates induced pluripotent stem cell (iPSC)-derived neurons carrying defined genetic variants and records how those variants alter neuronal firing and network activity. It then applies ML methods to integrate those functional readouts with genomic and molecular data, to link specific mutations to reproducible cellular phenotypes.
Researchers at the All India Institute of Medical Sciences (AIIMS) will collaborate with French institutional experts to develop AI-based diagnostic tools, especially for brain-related disorders. For this reason, the Indo-French Centre for AI in Health (IF-CAIH) at AIIMS New Delhi has been set up under a joint Memorandum of Understanding (MoU) signed by AIIMS-Delhi with Sorbonne University and the Paris Brain Institute, and they will initially focus on regenerative neurological disorders, including conditions such as Parkinson’s disease, and on neuromodulation and mental health (At AIIMS-Delhi, an Indo-French collaboration to use AI in brain research and diagnosis of neuro disorders).
KIMS Hospitals in India has become the first health centre in India to introduce Adaptive Deep Brain Stimulation (aDBS), a breakthrough in neurotechnology for Parkinson’s disease patients (KIMS Hospitals launches India’s first adaptive deep brain stimulation for Parkinson’s patients). Built on the Percept Platform (the Medtronic Percept Platform is a next-generation DBS system designed to treat movement disorders) and enhanced with BrainSense technology (by Medtronic designed to capture brain signals using an implanted DBS lead), the system can adjust stimulation levels in real time, responding to brain signals without manual intervention. Unlike previous DBS devices, which delivered constant stimulation, adaptive DBS detects fluctuations in brain activity and automatically increases or decreases stimulation, while specialist doctors define thresholds and parameters.
IXICO PLC (LSE:IXI, OTC:PHYOF, FRA:PYPB), the London-listed neuroscience imaging company, has published data showing that its AI-driven platform can measure brain shrinkage (key marker in the development of treatments for neurodegenerative diseases, including Huntington’s disease) at least as accurately as methods requiring analysis by human experts (IXICO says its AI brain imaging tool matches or beats human experts). IXICO said its platform proved the most sensitive method for detecting volume loss in both the whole brain and the caudate, a small structure deep in the brain that is affected early in Huntington’s disease.
✅ IXICO is a global leader in neuroimaging and biomarker analytics. IXI™ is IXICO's proprietary, AI-enabled neuroimaging technology platform for precision to help advance the treatment of neurological disorders and reduce the uncertainties associated with drug discovery, development, and monitoring.
The Korea Research Institute of Bioscience and Biotechnology (KRIBB) and a research team at the Natural Product Systems Biology Research Center of the Korea Institute of Science and Technology (KIST), have identified a 🆕 compound called Dokdothiocin from microorganisms found in Dokdo soil, which can reduce brain inflammation. KIST used its proprietary protein target prediction AI technology to predict that Dokdothiocin could block key pathways that regulate inflammatory signaling in the brain (Microorganism “Dokdothiocin” Discovered on Dokdo Offers Clues for Treating Brain Diseases).
✅ The joint research team discovered Dokdothiocin, a previously unreported compound, by diversifying the cultivation environment of Streptomyces so that it could produce 🆕 substances not typically generated. They succeeded in isolating and purifying this compound.
✅ Dokdothiocin has a highly unique structure, with 29 atoms connected in a ring formation. The research team emphasized that the structural rarity of this compound translates to high potential as a next-generation drug candidate that could overcome the limitations of existing therapies.
Researchers at the University of California, Santa Cruz (UCSC) have successfully “coached” lab-grown brain organoids to solve the “cart-pole” problem—a classic AI and robotics task of balancing a pole on a moving cart. By using reinforcement learning and electrical stimulation to provide feedback, the organoids increased their success rate from roughly 4,5% to 46% (Lab-Grown Brains Demonstrate Surprising Learning Abilities). This breakthrough demonstrates that living neural tissue has an inherent capacity for goal-directed, adaptive computation (Scientists Grew Mini Brains, Then Trained Them to Solve an Engineering Problem).
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